Rolling the Dice

This time map itself is worth checking out but the article connected to it makes it even better.

Tracing these alternative evolutionary paths, the researchers discovered that the protein – the cellular receptor for the stress hormone cortisol – could not have evolved its modern-day function unless two extremely unlikely mutations happened to evolve first. These "permissive" mutations had no effect on the protein's function, but without them the protein could not tolerate the later mutations that caused it to evolve its sensitivity to cortisol. In screening thousands of alternative histories, the researchers found no alternative permissive mutations that could have allowed the protein's modern-day form to evolve. The researchers describe their findings June 16, online in Nature.

"This very important protein exists only because of a twist of fate," said study senior author Joe Thornton, PhD, professor of ecology & evolution and human genetics at the University of Chicago. "If our results are general – and we think they probably are – then many of our body's systems work as they do because of very unlikely chance events that happened in our deep evolutionary past," he added.

As I read this, the notion of From It to Bit comes to mind as John Wheeler's astonishingly original concept of reality being an information appliance of infinite power, where all bits of reality constantly exchange information 24/7 via the laws of thermodynamics, not only makes sense but also gives a clear explanation as to how the multiverse works as a system.

Wheeler: It from bit. Otherwise put, every "it" — every particle, every field of force, even the space-time continuum itself — derives its function, its meaning, its very existence entirely — even if in some contexts indirectly — from the apparatus-elicited answers to yes-or-no questions, binary choices, bits. "It from bit" symbolizes the idea that every item of the physical world has at bottom — a very deep bottom, in most instances — an immaterial source and explanation; that which we call reality arises in the last analysis from the posing of yes-or-no questions and the registering of equipment-evoked responses; in short, that all things physical are information-theoretic in origin and that this is a participatory universe.

How cool is that? :)