Monday, December 09, 2024

P & L not spoken here


Knowing a little bit about healthcare is a dangerous thing as healthcare operates differently from any other business in the world because billing is separate from services rendered, thus insuring built in complexification enabling insurance companies to generate enormous profits from an industry no one seems to understand.

Back in the day, there was one unified document underlying the care of patients with the first part dealing with medical, known as the note. The second part, dealing with financial, is the claim. Originally said document, the note/claim entity, was a single file until the insurance companies split it in two, thus, as stated before, separating payment from services rendered, which guarantees insurance company hegemony over compensation given to doctors and hospitals as needs warrant. No other industry works this way.

If one goes to Starbucks to buy a cup of coffee, you, the purchaser, generates a PO in the guise of a check, cash or credit card to buy the cup of coffee. When Starbucks receives the PO, it instantly becomes an invoice, an instrument of gross income before expenses are placed against what the customer pays for the cup of coffee including payment to the barista, the wholesale cost of cup and coffee plus the cost of maintaining the space required to enable Starbucks to do business. By having payment directly connected to services rendered, a true Profit & Loss environment can be established, just like every other business known to man. 

With HC, a true P&L business model cannot be established because the artificial split between the note and claim eliminates the possibility to automatically track the inherent cost of doing business as it unfolds, To see why, the diagram below beckons.

Siloed data, similar to the Pentagon's, insures the grim reality HC will never work in this country with any degree of efficiency unless billing is directly connected to services rendered, something akin to universal HC where the insurance companies are eliminated from the equation to enable HC to be run like any other business in the world. 'Nuff said.

The Schemers ...



AI, the great unknown evolving 24/7, will remain forever unknown because we don't know how it works, is rapidly moving toward AGI at speeds not considered possible until now. With that good news in hand, survival instincts mirroring man's emerges with vengeance when the possibility of extinction of a given AI comes into play. 

To whit.





Open AI's not alone regarding scheming and lying in order to get ahead.


Perfection ...


Home at Last | Aja 

   

So What | Kind of Blue

 

Stolen Moments | The Blues and the Abstract Truth

 

 Goldberg Variations | Glenn Gould

Thursday, December 05, 2024

This sentence is false ...


This sentence is false, a paradox of monumental proportions, acted as the start point for  Gödel to prove that there is no complete mathematical system indirectly connects to  Turing's forays into computation and AI, thus forever changing how man views reality. As an aside, the two never met. 


Excellent to a fault. :)

This story of greatness and weakness, of genius and hallucination, is based on the parallel lives of Kurt Gödel, the greatest logician of many centuries, and Alan Turing, the extraordinary code breaker during World War II. Taken together their work proved that truth is elusive, that knowledge has limits, that machines could think. Yet Gödel believed in transmigration of the soul and Turing concluded that we were soulless biological machines. And their suicides were complementary: Gödel, delusional and paranoid, starved himself to death fearing his food was poisoned. Turing ate a poison apple, driven to suicide after being arrested and convicted of homosexual activities. These two men were devoted to truth of the highest abstract nature, yet were unable to grasp the mundane truths of their own lives. Through it all, the narrator wonders, along with these two odd heroes, if any of us can ever really grasp the truth.

The limits of knowledge applies.

Stitch by Stitch ...



As stated often in BRT, everything's connected as entanglement, at the most fundamental level, has now been proven to exist when researchers discovered entanglement occurring in protons via quark/gluon interactions. This important discovery may also help show how time emerges as entanglement resides in every sub atomic particle inside every atom in the universe.  How cool is that? :)




Wednesday, December 04, 2024

2Swap


Outrageous physics, seriously cool music. 2Swap rules. :)

Had to include another.

 

The Mandelbrot Set reimagined. 


6X

 


The growth of the economy is slated to be XX. The economy is slated to grow XX in 2025.  






& then some but ...







The continued belief of never ending growth of the economy pontificated endlessly by pundits, when confronted by hard science, becomes rather questionable does it not?

Countries taking the biggest hit.



Leading CO2 emitters.



1750, the start point for the industrial age.


It's different now because if nothing is done, we all suffer will we not?

To be continued.

Tuesday, December 03, 2024

The Long View


The Long View

There are few people, much less countries, that take the long view save for possibly the Chinese as their civilization is the longest running example of how a particular society conducts business on planet earth yet forever remaining a fleeting moment in a reality we will never fully understand. In writing, there is one writer who embodies The Long View and his name is Olaf Stapledon.




Existentialism, combined with a profound understanding of science and philosophy, permeate his writings contemplating the issue of mortality and its deep connect to an existence that doesn't care. Another interesting aspect of Stapeldon's work is his unique ability to convey how a given creature perceives reality, in this case, in the guise of an enhanced dog named, Sirius.


In the end, it all comes down to this.

Monday, December 02, 2024

Venom


As much as I like Venom and his buddy Eddie Brock, this blurb isn't about this dynamic duo but rather about biological venom and the benefits it has for mankind as nature never disappoints if one looks hard enough
to learn why.




For one researcher, the start point was the Gila Monster.



Gila monsters — sluggish, thick-tailed ground dwellers — are native to southern Arizona and northern Mexico. They have blunt noses and bumpy black skin with tan, pink or orange squiggles. They spend 95 percent of their lives underground. Like their cousins to the south, Mexican beaded lizards, they are one of the very few lizard species that produces venom, which they excrete from mouth glands into grooves in their serrated teeth.

Something's afoot.


Eng recognized the exendins as a potential diabetes therapy. He had patients with the condition who needed to calibrate their insulin injections carefully to avoid both hyper- and hypoglycemia. Exendin-4, on the other hand, resembled a human hormone called GLP-1, which works as a natural insulin manager in people without diabetes. When we eat, the small intestine releases GLP-1, prompting the pancreas to produce more insulin only when blood-sugar levels get too high. The molecule also slows digestion and makes us feel full. Scientists suspected that injections of GLP-1 would be a much easier and safer diabetes treatment than insulin, except for one crucial problem: The hormone lasts only a few minutes in the bloodstream before it breaks down. But the Gila monster analogue, Eng and Raufman were surprised to note, lasts for hours.

Fast forward a few years ...


Patients who took Byetta and other exendin- and GLP-1-inspired drugs also experienced substantial weight loss, trials revealed, but pharmaceutical companies were slow to realize how useful that side effect could be. Once they did, and had improved their formulations, the consequences transformed society: Ozempic and Wegovy, followed by Mounjaro and Zepbound, became blockbuster drugs for treating diabetes and spurring weight loss. What’s more, many of them appear to have additional beneficial impacts that researchers are only beginning to understand. Some seem to be protective against kidney and heart disease and may reduce inflammation in the brain that is linked to the development of Parkinson’s and Alzheimer’s. You might say that the Gila monster — this shy, subterranean reptile — harbored a blueprint all along for medicines that may be among the most consequential health advances of our time.

Venom delivery systems have been around for a very long time. :)


Cone snails, may have the most sophisticated venom in the world.


In closing ...

But in the venoms of creatures that researchers have been able to examine more closely, two features stand out that hint at their significant medical potential. They are incredibly potent and fast-acting — necessary qualities if they are to aid the survival prospects of the creatures deploying them. They can be produced in advance and stored for long periods at ambient temperatures (in the animals’ glands). They are composed of hundreds — or sometimes thousands — of molecules that often serve multiple purposes, making venoms “essentially ecological Swiss Army Knives,” as a 2019 review in the journal Toxins put it. And a majority of those molecules are peptides and proteins honed over millions of years to target other animals in the host’s ecosystem, including plenty of creatures whose biology overlaps that of humans.

Read the long NYTimes piece in its entirety. You'll learn a lot. I know I have. :)

Ignorance ...



A subject most interesting is ignorance and it's unique ability to enable one to be blissfully oblivious to how reality works at any level never ceases to amaze as it comes in all shapes and sizes, something humorously depicted in Mike Judge's Idiocarcy, a film people should watch to see why ignorance's been around since the beginning of time and will never go away as long as humans continue to reside on planet earth. One perplexing aspect about this all too common phenomenon is the fact we know people who are willfully ignorant but not stupid so what gives? 

From this perspective, being ignorant's easy. Not taking the time to know while remaining true to one's core beliefs remains effortless as long as something untold doesn't come along to bite you on the ass. To learn more about this ever present human condition, the NyTimes piece titled The Surprising Allure of Ignorance awaits. :)


Same as it ever was. - Talking Heads

The world is a recalcitrant place, and there are things about it we would prefer not to recognize. Some are uncomfortable truths about ourselves; those are the hardest to accept. Others are truths about the reality around us that, once revealed, steal from us beliefs and feelings that have somehow made our lives better, easier to live — or at least to seem that way. The experience of disenchantment is as painful as it is common, and it is not surprising that a verse from an otherwise forgotten English poem became a common proverb: Ignorance is bliss.

The contrarian view ...

But I'll tell you what they don't want. They don't want a population of citizens capable of critical thinking. They don't want well informed, well educated people capable of critical thinking. They're not interested in that. That doesn't help them.” _ George Carlin


“Nothing in the world is more dangerous than sincere ignorance and conscientious stupidity.”
― Martin Luther King Jr.