Rewired ...

Brains adapt just as life adapts when faced with different environments, something readily seen with astronauts dealing with weightlessness.

Brains of Cosmonauts “Rewired” During Space Missions

A new study published in Frontiers in Neural Circuits is the first to analyze the structural connectivity changes that happen in the brain after long-duration spaceflight. The results show significant microstructural changes in several white matter tracts such as the sensorimotor tracts. The study can form a basis for future research into the full scope of brain changes during human space exploration.

Our brain can change and adapt in structure and function throughout our lives. As human exploration of space reaches new horizons, understanding the effects of spaceflight on human brains is crucial. Previous research has shown that spaceflight has the potential to alter both the shape and function of an adult brain.

The tech used ...

To study brain structure and function after spaceflight, the researchers used a brain imaging technique called fiber tractography. 

“Fiber tractography gives a sort of wiring scheme of the brain. Our study is the first to use this specific method to detect changes in brain structure after spaceflight,” explained Wuyts.

Wuyts and his team acquired diffusion MRI (dMRI) scans of 12 male cosmonauts before and right after their spaceflights. They also collected eight follow-up scans, seven months after spaceflight. The cosmonauts all engaged in long-duration missions of an average length of 172 days.

The researchers found proof of the concept of ‘the learned brain’; in other words, the level of neuroplasticity the brain has to adapt to spaceflight. “We found changes in the neural connections between several motor areas of the brain,” said first author Andrei Doroshin, of Drexel University. “Motor areas are brain centers where commands for movements are initiated. In weightlessness, an astronaut needs to adapt his or her movement strategies drastically, compared to Earth. Our study shows that their brain is rewired, so to speak.”