40-60 ...

Aging sequence

We all die but you know that, right? In two terrific pieces in Earth.com, researchers pinpointed the approximate stages where the inevitable happens, even to rubes like me. Interesting to say the least. :)

As humans, we see aging when we look in the mirror, but the crucial changes happen in the proteins that keep every tissue running. Those proteins rise, fall, and shift as the years stack up, shaping organ function and health over time.

A large study recently published in the journal Cell follows protein patterns across the human body to map when and where aging speeds up.

This research tracks the molecules that build structures, relay signals, and handle cleanup inside cells, where wear and tear accumulates.

By watching proteins rather than just reading genetic instructions, the study offers a more direct view of how organs change across adult life.

The pace of change isn’t uniform across the body. The starkest shifts clustered between 45 and 55, when many tissues remodeled their protein profiles.

Within that window, the aorta showed the most marked change, and the pancreas and spleen exhibited sustained shifts that stood out against more gradual patterns elsewhere.

09-05-2024 - Earth.com

Time frames

By studying the biological data of 108 people aged between 25 and 75, the team identified 135,000 changes in various molecules and microbes within our bodies.

Their results showed a whopping 81% of these molecules showed drastic shifts around the ages of mid-40s and early 60s. According to Snyder, this is a game-changer in anti-aging research.

Any questions? :)